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Proteinuria after Renal Transplant: Causes and Treatment

Proteinuria after Renal Transplant: Causes and TreatmentProteinuria is highly prevalent after Renal Transplant, occurring in over 45 percent of post-transplant patients per year. Generally, the level of protein in urine is less than 500 mg/day. In this text, let's look at he causes and treatment of proteinuria after Kidney Transplant.


There are a variety of causes of proteinuria after Renal Transplant, which can be divided into immune or non-immune factor. Moreover, the cause is different in the early and late stage of transplantation as below:

Early: ischemia-reperfusion injury, long cold ischemic time, delayed recovery of the function of tranplanted kidney, acute rejection reaction, drug poisoning like CNI, etc.

Late: high blood pressure, Diabetes, chronic rejection reaction, new development or relapse of glomerulonephritis, chronic allograft nephropathy (CAN), chronic drug poisoning like CNI, inadequate of nephrons, etc. In addition, some drugs like sirolimus may induce or aggravate the urine protein.


Since there are many causes of protein in urine after Renal Transplant listed as above, it is necessary to confirm the exact reason so as to take corresponding and effective strategies to eliminate this problem. You can consult your doctor for personalized advice or feel free to make an appointment with our kidney experts for free and specific analysis!

Clear Blood Pollution Therapy is recommended for people with post-transplanted Kidney Failure. This therapy can help protect the new kidney from being further damaged as well as improve the overall renal function. In this way, both patient's life quality and life expectancy can be significantly improved! If you still have any question or need any help, feel free to chat with our online doctor!

  • Tag: Protein in Urine
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