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Polycystic Kidney Disease: Creatinine Level From 1.78 to 5.62 and Kidney Transplant

Here is a reply from our expert to a PKD patients who attached his medical report. His creatinine leve increases from 1.78 to 5.62 and wondered whether kidney transplant is a good choice.

I read your email and discussed your condition with our experts on PKD and Renal Failure just now, the following are our suggestions.

Firstly, PKD usually is found at one's 30s and patient will have high blood pressure when they 40s. The disease will aggravate into Renal Failure in one's 50s. According to your medical history, your disease aggravate rapidly, but it seems there is no effective treatment. Your creatinine increases from 1.78 to 5.62 and clearance decreases from 48 to 11 though you are keeping treating it. You start dialysis just in 5 years. why?

There are two reasons. On one hand, there is no specific treatment for PKD. If we leave the cysts alone, they will surely enlarge, then do harm to kidney function. On the other hand, you are not clear about the cause of your disease. The high creatinine, low clearance, low HB and so on are all caused by the decreasing on kidney function, but there is no treatment for renal function.

Secondly, Marcelo, according to our clinical experience, your GFR (glomerulus Filtration rate ) is about 11-13. It is a little earlier for your start dialysis, but early dialysis can protect your remaining renal function, which provide a good basis for your further treatment. Please let me know your urine volume in 24 hours and your heart condition,then we will make treating plan for you.

Finally, to your condition, we don't suggest kidney transplant. You know, PKD is a genetic disease, 91% patients will have PKD again after transplant and the transplanted kidney can survival only for about 3 to 5 years. Now, your condition is not so serious, if you take time for treatment, there are great hope for treating the PKD as well as improving kidney function. We are glad to help you, please let us know your idea on treatment.

  • Tag: PKD Treatment
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