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Stage 4 PKD: Unexplained Joint Pain And Swelling

Stage 4 PKD: Unexplained Joint Pain And Swelling For patients with polycystic kidney disease (PKD), their disease can cause many problems in their body, which can lead to many symptoms. And joint pain and swelling are very common.

For patient with stage 4 PKD, his kidney has been damaged by his disease severely, and his kidney function has also been lowered obviously.

1.Joint pain

Joint pain can be caused by many factors, like gout, renal osteopathy, the side effects of medicine. And these factors are very likely to be met by patient with stage 4 PKD.

If patient’s joint pain is caused by gout, which is due to high uric acid. Uric acid can form urate crystal, and that can accumulate in patient’s joints, which can cause joint pain.

When patient’s PKD has progressed into the late stage, a severe complication in patient’s body is renal osteopathy, and that can also cause pain in patient’s joint.

Besides, patients with PKD will need to take lots of medicines, while some hormone medicines have many side effects, and that may lead to bone problems like osteoporosis.


Swelling in patient with kidney disease is mainly caused by two major reason. One is massive proteinuria, and the other is the retention of sodium and fluid in body.

Patient with PKD may not have obvious swelling when he is in the early stage, because PKD usually does not cause massive proteinuria. But when patient’s disease has progressed into the late stage, which means patient’s kidney function has been damaged severely, it is very likely for him to have swelling. Because a major function of kidney is filtrating fluid, so when patient’s kidney function is low, there will be lots of fluid accumulating in patient’s body, which can lead to edema.

These are the reasons of joint pain and swelling in patient with PKD, and if you have any other problem in dealing with PKD, you can juts leave us a message, and we will do what we can to help you, or provide the guidance you need.

  • Tag: PKD Symptoms
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