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How Can ADPKD Skip a Generation

How Can ADPKD Skip a GenerationHow can autosomal dominant polycystic kidney disease (ADPKD) skip a generation? If the affected woman or man wants to have a healthy baby, they must consider this question.

It is reported that about 85% of ADPKD patients have an abnormal gene on chromosome 16, and other patient’s abnormal gene is on chromosome 4. Because this disease is autosomal dominant, every child of one parent who has this disease has a 50% chance of getting ADPKD. Even though one in every two children in theory has this type of Polycystic Kidney Disease, sometimes both or neither will be diagnosed with this disease.

Can ADPKD skip a generation? If the abnormal gene isn’t inherited by one person from his or her parent, it is impossible for this person to pass ADPKD to his or her child. That is to say, once ADPKD can be prevented, descendant usually won’t have this disease. However, rather than skipping a generation, some people who have ADPKD don’t show any symptom or complication before death, but then their children are tested out this disease. This can mistake us that ADPKD indeed can skip one generation.

How to get a healthy baby for ADPKD patients? If enough fortunately, one Polycystic Kidney Disease patient with one healthy person can get a healthy baby spontaneously. In fact, they can still do something to increase this fortune. For example, genetic testing and some antenatal care can help detect the onset of abnormal gene in advance. However, we can’t promise the success rate can be 100%.

If you are experiencing autosomal dominant polycystic kidney disease and preparing to have a baby, you should also accept some treatments to control your complications and shrink your kidney cysts. Your good health condition can make you have a baby more safely. You need any help? Just email to or leave a message below.

  • Tag: PKD PKD Basics PKD Prognosis
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