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Top 10 Facts About Polycystic Kidney Disease in America

Polycystic kidney disease is one of the most common life-threatening genetic diseases, which runs and spread in families. Here are the top 10 facts about polycystic kidney disease.

●More than 600,000 Americans and 12.5 million newborns, children and adults worldwide battle Polycystic Kidney Disease (PKD) every day.

●Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted in end-stage renal disease (ESRD) by age 53, on average, and was responsible for 6 percent of ESRD cases in the U.S.

●ADPKD is one of the most common life-threatening genetic diseases, affecting 1 in 500 worldwide. Parents with the dominant form of PKD have a 50 percent chance of passing the disease on to each of their children.

●The average age for development of ESRD for patients with ADPKD has increased from 53 to 57 years of age. ADPKD is currently responsible for 4.5 percent of overall ESRD cases and 2.2 percent of new ESRD cases each year in the U.S.

●When dominate, the condition develops and shows symptoms when an adult is in their 30s, although in some cases children have been known to develop the disorder. Most cases, about 90 percent, are autosomal dominant polycystic kidney disease (ADPKD).

●ARPKD is a relatively rare form of PKD that affects 1 in 20,000 babies and often leads to death in the first month of life. Parents who carry the ARPKD gene have a 25 percent chance of passing the disease on to each of their children.

●Over time, these cysts grow and multiply, causing the kidney to increase sometimes dramatically in size. Although a normal kidney is roughly the size of a human fist, PKD kidneys can grow to be the size of a football or larger and weigh as much as 38 pounds each.

●Urinary tract infections (UTI) and kidney stones are common among people with PKD. About 20% to 30% of people with PKD develop kidney stones. High blood pressure occurs in about 60% to 70% of people with PKD and for many is the first sign of the disease.

●Kidney transplantation is widely available, and nearly 13 percent of ADPKD patients who develop ESRD receive a transplant before beginning dialysis therapy. Limited organ availability has resulted in longer waiting times.

●Transplant failure due to acute organ rejection is much less common, with one-year success rates exceeding 90 percent.

If you need more info about Polycystic Kidney Disease facts on your own country or region, you are suggested to leave a message below and we are glad to send you the best answer.

  • Tag: PKD Basics
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