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Polycystic Kidney Disease: Cause, symptom, Treatment

Polycystic Kidney Disease: Cause, symptom, TreatmentPolycystic kidney disease (PKD) is a common chronic kidney disease. PKD is a progressive kidney disease, and it can damage kidney structure gradually, which can lead to kidney failure in the end.


Polycystic kidney disease is a genetic disease of kidney. It is divided into autosomal dominant PKD (ADPKD) and autosomal recessive PKD (ARPKD), and PKD in patients mainly belongs to ADPKD, while ARPKD is less common.

For patients who have ADPKD, his child will have 50% chance to develop this disease.

While ARPKD is a rare disease, but it can cause severe and quick disorders, and it usually causes death in child.


·Kidney pain: this is the most obvious symptom in PKD patients, and it will be more obvious as patients’ disease progresses.

·Kidney cyst: patients will have kidney cyst, and the size and quantity will increase over time.

·Hypertension: as the cysts grow, they can oppress patients’ kidney, and that will promote the excretion of renin, which can cause patients have high blood pressure.

·Hematuria: PKD patients usually have blood in their urine, and that may be caused by infection, kidney stone, angiorrhexis, and so on.

·Kidney stone: kidney stone is a symptom that often appears in patients with PKD, and the ratio is about 20%.

·Renal insufficiency: this disease will cause renal insufficiency sooner or later, but most patients may not have the decrease of kidney function before forty years old.


For patients in the early stage of PKD, they may need no treatment, because it will not cause any problem to patients’ health. And in this stage, patients should take good care of themselves in their life, which is very helpful to slow down the progression of PKD.

When patients’ disease is severe, they will need surgery to relieve their condition, and they will also need treatment to control the complications like hypertension, kidney stone, hematuria, etc. While if the cysts are too severe, patients may need to take dialysis or accept kidney transplant.

These above are some basic points about PKD, and if you have any question, you can contact us, and we are willing to help you.

  • Tag: PKD Basics
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