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Why Patient With Lupus Nephritis Often Has Severe Edema

Why Patient With Lupus Nephritis Often Has Severe Edema

Patient with lupus nephritis often has obvious edema, while sometimes it is a scary symptom. And why patient with lupus nephritis often has severe edema?

Edema in patient with lupus nephritis may firstly appear around patient’s eyes or in patient’s legs. While patient is very likely to have severe edema, like pulmonary edema, which can cause patient to feel hard to breath.

What are the causes of patient’s edema?

Edema is mainly caused by two reasons. One is the retention of fluid and sodium in patient’s body, and the other is the massive loss of protein.

The retention of fluid and water is more likely to appear in patient who is in the late stage of lupus nephritis, at which stage patient’s kidney function is damaged severely, and patient’s GFR is low, so the excess fluid will accumulate in patient’s body, and lead to edema. On the other hand, massive proteinuria means there is lots of protein leaking out from patient’s blood, which will reduce the osmotic pressure in patient’s blood, and the fluid in patient’s blood will flow into his tissue space, which will lead to edema.

Why patient with lupus nephritis often has severe edema?

Lupus nephritis is caused by the accumulation of immune complexes in patient’s glomeruli, which will damage patient’s glomeruli. While the damage in patient’s glomeruli will increase the permeability of filtration membrane, which will cause patient to have massive proteinuria.

Besides, proteinuria can aggravate patient’s kidney damage obviously, and when patient’s disease progresses into the late stage, patient’s lower kidney function will increase the severity of edema. So it is more likely for patient to have severe edema.

Edema is a symptom that can aggravate patient’s condition severely, so patient should take measures positively to cope with this problem.

In the end, if you have any problem on lupus nephritis, you can contact our online experts, and we are glad to help you.

  • Tag: Lupus Nephritis Symptoms
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