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Can Diuretic Cause High Creatinine Level

Can Diuretic Cause High Creatinine LevelSerum creatinine level is blood test item used commonly to indicate how well kidneys are functioning. In addition to kidney damage, dehydration, overwork and strenuous exercise can also cause high creatinine level. Diuretic is one medication that can help increase urine output and alleviate some kidney disease complications. Can diuretic help lower high creatinine level or cause high creatinine level?

High creatinine level

Creatinine is one waste product produced during muscle metabolism. Normally, healthy kidneys can maintain the balance of creatinine production and excretion. However, if creatinine formation increases suddenly, serum creatinine level will increase. This is called transient high creatinine level. However, if kidneys are damaged, creatinine level will keep in the high level persistently.


Diuretic is one medication that is often used to help damaged kidney cells to remove extra fluid. This means this medicine can help alleviate symptoms and problems caused by fluid retention, for example, high blood pressure and swelling. However, this medication may also have some side effects.

Can diuretic cause high creatinine level?

Yes. Diuretics like furosemide indeed can lead serum creatinine level to rise. This is because, long-term use of diuretics can cause the kidneys’ overwork to compensate that can prompt the resorption of sodium. This will lead to further kidney damage. That is to say, diuretic can be one reason of elevated creatinine level, especially when high creatinine level is caused by kidney damage and dehydration.

In addition to diuretic, some other medications like NSAID may also lead creatinine level to increase. If your creatinine level is higher than 1.2mg/dl, you should pay highly attention to your medication use. In this case, you should also take some medications such as ketosteril, Medicated Bath, Enema Therapy, Acupuncture, and so on. Check with the doctor online to determine which therapy is best for you.

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