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Why Fatigue Appears In Patient With High Creatinine

Why Fatigue Appears In Patient With High CreatininePatient with kidney disease often has high creatinine, and for patients with high creatinine, most of them will notice fatigue in their body.

Why patient has high creatinine?

High creatinine is a common condition in patient with kidney disease, which often indicates severe kidney damage.

Creatinine should be filtrated out by kidney, but when patient’s kidney function is lowered by his disease, and when the damaged kidney function reaches a certain degree, patient will have high creatinine.

In fact, kidney has strong metabolic ability and compensation, and patient will not have high creatinine unless more than half kidney function is damaged, which is very severe.

Why fatigue often appears in patient with high creatine?

As we know, high creatinine means patient’s kidney function is damaged severely. And another major function of kidney is excreting hormones, among which hemopoietin is very important for producing red cells.

So, when patient’s kidney structure is damaged, its function of excreting hemopoietin will also be lowered, which will affect the quantity of red cells. While red cells can transport oxygen for our body’s metabolism, so when its quantity is reduced, the produced energy for our body tissues will also reduce, which can cause patient to have fatigue.

Besides, if patient’s creatinine level is very high, that may indicate patient’s condition is very severe, and patient’s kidney disease has progressed into the late stage. At this point, there will be lots of toxins accumulating in patient’s body, which can damage the process of medullary hematopoiesis and shorten the survival time of red cells, and that can aggravate patient’s fatigue.

Thereby, there is no direct relation between high creatinine and fatigue, but these symptoms indeed have relationship.

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