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Drugs to Treat FSGS Kidney Disease

Drugs to Treat FSGS Kidney DiseaseIf uncontrolled effectively, FSGS may aggravate into end stage renal failure easily. In order to avoid ESRD, FSGS patients need to take correct drugs timely. At present, what drugs are effective to treat FSGS kidney disease?

The causes of focal segmental glomerular sclerosis

The onset of FSGS can be related to several pathogenic factors such as poisoning damage, abnormal humoral changes, hemodynamics disorders, and immune disorders. According to FSGS patients’ test report, FSGS patients are found to have many immune complexes such as C3, C1q, IgM and IgA within the kidney sclerosis. From this point, the following drugs are used commonly to treat FSGS kidney disease.

Drugs or medications to treat focal segmental glomerular sclerosis

1. Glucocorticoid

Before patients are resistant to steroids, they should take prednisone in advance. Generally, patients can get remission in 3-4 months. If adults with FSGS don’t get remission after six months, we call it hormonal resistance. For the elder with FSGS, most doctors recommend them to take prednisone therapy every other day for 3~5 months. However, if patients don’t respond to glucocorticoid, they should take some other medications.

2. CsA and FK506

Most often, FSGS patients can find their protein in urine reduces after six months’ usage of cyclosporin (CsA), but this disease relapses easily when patients reduce their dosage or stop their medications. Besides, patients should pay attention to monitor their serum creatinine level and modify their dosage timely, because these medications have renal toxicity.

3. Cytotoxic agents

These medications can be used as the secondary treatment, but the therapeutic effects should be observed carefully.

4. Plasma Exchange and Immune Adsorption

These two therapies can exchange immune complexes and waste products with essential nutrients. Generally, patients’ kidney disease can be relieved a lot, after their blood is purified repeatedly.

5. Immunotherapy

This therapy focuses on removing pathogenic factors and rebuilding kidney structure at the same time. As long as the internal environment becomes normal and kidneys return to work again, they don’t need to bear this disease any more.

The individual treatment plan should depend on patients’ illness condition. To learn more about them, you can consult the doctor online or leave your questions in the form below.

  • Tag: FSGS Kidney Disease Treatment FSGS Treatment Immunotherapy
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