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Focal Segmental Glomerular Sclerosis (FSGS) is a kidney disease which will cause damage in patient’s glomeruli focally and segmentally, and it is a major cause of nephrotic syndrome, which can cause severe damage in patient’s kidney.
When patient’s kidney function is damaged severely, his creatinine and urea level will be elevated. In fact, the levels of urea and creatinine are two major measures to reflect patient’s kidney function.
What is the normal levels of urea and creatinine ?
Creatinine is the metabolic wastes of muscle, and urea is a major metabolic product of protein, and these substances should be filtrated out by our kidney.
Creatinine can be gotten from our body muscles and diet persistently, and protein can be gotten from our diet all the time, so urea and creatinine will be produced in our body persistently. At the same time, our body will also filtrated out them from our body persistently. So, the levels of urea and creatinine change in a stable range.
For healthy people, their creatinine level changes from 0.5mg/dL to 1.3mg/dL, and urea level changes 9~20mg/dL.
What can we know if patients with FSGS have elevated urea and creatinine?
Many factors can cause patients to have elevated creatinine and urea, but when they are caused by kidney damage, they will be persistent, and they are dangerous signs.
For patients with FSGS, their disease will damage their kidney function, and when their kidney function is low enough, lots of urea and creatinine will accumulate in kidney.
In fact, our kidney has strong metabolic ability and compensation, and half normal kidney function will be able to guarantee our body health. Thereby, patients with FSGS will not have high urea and creatinine until more than half kidney function is damaged.
If the levels of urea and creatinine are higher enough, that may even indicate patients have kidney failure, which means dialysis will be needed.
Kidney disease is very dangerous, so patients should do their best to improve their condition. And if you need any help, you can leave us a message about your condition and problem, so we can provide the guidance or do what we can to help you.
