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Chronic Kidney Disease and Risk of Cardiovascular Disease

Patients with Chronic Kidney Disease is more likely to develop cardiovascular disease than others. Cardiovascular disease accounts for more than half of all deaths among people with kidney failure.

Cardiovascular Diseases Which May Occur in Patients with CKD

- Heart Failure: A strong heart pumps blood throughout the body. A weakened heart is unable to do an efficient pumping job. If a heart cannot pump enough blood, heart failure may occur.

- Coronary Atery Disease: Coronary artery disease can also lead to other problems such as chest pain (angina).

- Heart Attack: A heart attack occurs when a coronary artery, which carries blood and oxygen to one section of the heart muscle, is blocked.

Risk Factors for CKD Patients to Develop Cardiovascular Disease

High blood pressure

Kidneys are important organ to regulate blood pressure by controlling renin production. When kidneys are failed, it may release too much renin, which can leave to high blood pressure.

High blood pressure means the blood shows extra force to the blood vessels. When the force keeps increase, it may cause damage to the blood vessels in each organ, including heart.

High homocysteine level

Homocysteine is an amino acid normally found in blood. Healthy kidneys regulate the amount of homocysteine in the blood and remove any excess. High levels of homocysteine may also damage the lining of the blood vessels, making a person prone to blood clots which increase the risk of stroke and heart attack.


Anemia means your body fail to produce enough red blood cells. Kidneys can manufacture a hormone named erythropoietin which helps increase the production of red blood cells. Once your kidneys cannot function well, shortage of erythropoietin will cause anemia.

Without enough blood and oxygen supply, a person may develop heart attack.


Diabetes means high blood sugar, which may cause blood vessels damage in many organs. Thereby, it may affect kidneys (Diabetic Nephropathy) and heart, causing cardiovascular disease.

  • Tag: CKD symptoms
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