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Symptoms Of End Stage Renal Disease

Symptoms Of End Stage Renal Disease

When patients’ glomerular filtration rate is under 15ml/min, it means patients are in stage five renal disease, which is namely the end stage. Patients with end stage renal disease have severe kidney damage, and many symptoms will appear in this time.


Patients will often feel tired in end stage renal disease, and it is mainly caused by anemia.

Kidney can excrete hemopoietin, but when kidney is severely damaged, this function will also be damaged. Thereby, the amount of hemopoietin excreted will be much less than its normal value, so the red cells produced will also be much less. As we know, red cell can take oxygen to body cells which will be used for their metabolism. If there is no metabolism, there is no energy for people’s activity, and that is why patients always feel tired.


Edema is a very common symptom to patients in end stage renal disease. In this time, patients with slight edema will have edema in their ankles, and some patients who have severe edema may find it is hard for them to breath.

Urine changes

Another common complication is the urine changes. Patients in end stage renal disease may have small foams in their urine surface, and that will not disappear in a short period. Patients may also find they have colored urine, and their urine color may be red, tea colored, brown, and so on. Besides, patients may also find they have frequent urination at night.

Nausea and vomit

Patients in end stage may often have nausea and vomit. As we know, patients’ kidneys are damaged severely in the end stage of renal disease, so there is lots of urea accumulating in blood. If the level of urea is high, it will be decomposed by a kind of bacteria in gastrointestinal tract, and then ammonia will be produced. Ammonia can stimulate our gastrointestinal system, so patient will often have nausea and vomit. Besides, another common reason that cause nauseas and vomit is edema in patients gastrointestinal system.

Besides, patients may have many other symptoms in the end stage of renal disease, such as kidney pain, sleep problem, loss of appetite, nervous problems, and so on.

Patients in end stage of renal disease is in severe condition, so they should follow their doctors’ arrangement positively, and it is very important for them to keep a good emotion in this condition. In addition, if you need any help, you can also contact us, and we are willing to help you.

  • Tag: Chronic Kidney Disease Symptoms
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