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What Is The Relationship Between Creatinine and GFR

What Is The Relationship Between Creatinine and GFRCreatinine level and glomerular filtration rate (GFR) are two common standards in medicine to judge patient’s kidney condition, and we often hear patient’s GFR may decrease when patient’s creatinine level rises to some certain degree. While what is the relationship between creatinine and GFR?

Creatinine is a metabolic waste of muscle, and it is a toxin to our body, which should be excreted out by our kidneys, and it will not be reabsorbed back to blood by kidney tubule, so it can reflect patient’s kidney condition. In normal condition, almost all creatinine produced by our body will be excreted out by our kidneys in the same day.

GFR is about how much filtrate can be produced by people’s kidneys in unite time. Healthy people’s GFR is about 125ml/min, while if a person’s GFR is more than 90ml/min, it is also thought to be normal.

Both of creatinine level and GFR are reflections of patient’s kidney condition. In fact, creatinine level is not an accurate way to reflect patient’s kidney condition when patient is in the early stage of kidney disease. Our kidneys have strong compensation, and there will not be any obvious problem caused by kidney disease if only more than half kidney function is normal. Thereby, even if patient already has kidney damage, patient’s creatinine level may not have obvious rise.

Kidney disease is divided into five stages according to patient’s GFR. For patients who are in stage 1 and 2, they do not have obvious creatinine level rise caused by kidney damage. While when patient is in stage 3, in which patient’s GFR is between 30ml/min to 59ml/min, and patient’s kidneys are not able to complete their work normally, so creatinine will accumulate in patient’s blood gradually in this time.

Starting from stage 3, patient’s GFR will go on decreasing, and patient’s kidney function will reduce continuously, and more creatinine will be accumulated in patient’s blood, which will cause patient to have higher creatinine level.

While these are the basic relations between creatinine and GFR. In the end, if you still have any doubt, you can contact us, and we are willing t help you.

  • Tag: Chronic Kidney Disease Basics
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