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SLE Kidney Disease for 12 Years, High Creatinine Level, High BUN Level

Posted: by safia      Time: 2013-04-05 17:04

Topics: Lupus Nephritis High Creatinine Level

Details: My name is safia and I have SLE for more than 12 years. I suffer from high creatinine level and high BUN level also. I attach my test report, can you do me a favor?

Expert Answer
I have analyzed your reports. Obviously, your condition was firstly alleviated and then there was a relapse. I notice that the medicine dosage has already been reduced to low level for stablizing your condition. In short, the lupus factor is now under control and the main problem exist in interstitial area.

Based on your biopsy test report, there are partial sclerosis of glomeruli. Generally speaking, only when overall kidney function has declined by 50% to 60%, will serum creatinine level start to exceed normal range. The sclerosis portion is not that serious to account for 50% to 60%. The most possibility exist in Tubular atrophy and interstitial fibrosis. In short, the damage in renal tubules will also draw back glomerulus' function in filtrating blood.

In another word, renal tubule and renal glomerulus can influence each other in terms of function ability. The biopsy test report show inflammatory cellular infiltration, which is an Independent dangerous factor that indicate poor prognosis.

This is my opinion about your Lupus Nephritis and High Creatinine Level. Any follow up, please leave a message.

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