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Diffuse Mesangial Proliferative Glomerulonephritis with IgA Disease

Posted: by zhaoshaoning      Time: 2014-05-11 02:21

Topics: IgA Nephropathy

Details: Can you kindly help to explain the below please? My father’s test report shows diffuse mesangial proliferative glomerulonephritis with global sclerosis, consistent with IgA disease. What does it mean?

Expert Answer

From your description, we can know your father has IgA Nephropathy. To diagnose IgA Nephropathy, kidney biopsy is a must. The diagnosis characteristics are common diffuse mesangial or focal segmental proliferative glomerulonephritis and IgA immune complexes depositing in glomerular mesangial area.

Moderate or severe proteinuria usually indicates diffuse mesangial proliferative glomerulonephritis, accompanying crescent or glomerular sclerosis. Besides, gross or microscopic hematuria is one common symptom of IgA Nephropathy. Therefore, your father may also present proteinuria and hematuria.

IgA Nephropathy is one immune disorder that may progress into kidney failure eventually. From this point, you should take your father to accept effective treatments for controlling your father’s condition timely.

Since IgA Nephropathy is due to immune problem, we would like to introduce Immunotherapy. With six intimated linked steps, this therapy can not only remove IgA immune complexes but also repair damaged kidney cells and regulate immune system. Therefore, it is able to prevent the relapse of IgA Nephropathy effectively.

However, this doesn’t mean all patients can get benefits from this therapy. To determine whether your father can use this therapy, send the latest test report to or describe your illness condition for online doctor.

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