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Treatment of Recurrent IgA Nephropathy after Kidney Transplant

Treatment of Recurrent IgA Nephropathy after Kidney TransplantIgA Nephropathy is the commonest cause of glomerulonephritis worldwide. Kidney Transplant is the treatment option for individuals with ESRD due to progressive IgA kidney disease. Is there any treatment for recurrent IgA Nephropathy after transplant? Our online doctor is available to offer you advice for free if you like to talk.

High recurrence rate of IgA Nephropathy after kidney transplant

IgA Nephropathy recurs commonly after a kidney transplant. If post-transplanted patient with IgAN did a kidney biopsy, approximately 60% of them would have evidence of the disorder in the biopsy specimen. About 20-40% of patients actually have abnormal protein or blood detected in the urine due to recurrent IgA Nephropathy. On average, the recurrent often happens around 2.5 years after the kidney transplant.

Reason for recurrent IgAN after kidney transplant

IgA Nephropathy is a kind of autoimmune disease. When the IgA antibody fails to work normally, large amount of immune complexes will be produced with over-reactive immune response, then the immune complexes deposit on the glomeruli, causing inflammation and glomeruli damage. Kidney function is damaged gradually. Even though kidney transplant is done, patients' immune system is still deficient or disordered, so there are still immune complexes, then the glomeruli are injured just like before. That's the reason who the transplanted kidney is also injured after several years.

Treatment of recurrent IgA Nephropathy after kidney transplant

For patients who want to protect their new kidney and avoid Dialysis or second transplant, they are suggested to get treatment to regulate immune system, remove immune complexes, enhance the self-heal ability of the kidney, and improve kidney function.

If you or your beloved one has transplanted kidney failure due to recurrent of IgA Nephropathy, you can email us at with your detailed condition. The best treatment plan will be offered for your reference.

  • Tag: IgA Nephropathy Treatment
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