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Iga Nephropathy: Improve Kidney Function to Avoid Dialysis

Iga Nephropathy: Improve Kidney Function to Avoid DialysisIn western countries, the concept of treatment for IgA Nephropathy is: In the early stage, they do not have a positive attitude to treat the disease but only give some drugs to relieve symptoms. Then they will wait the progression of the disease till the End Stage Kidney Failure. By then, dialysis or kidney transplant has to be adopted. In China, we adopt a very different concept and we insist to treat IgA Nephropathy in the early stage so as to help patients improve kidney function and avoid Dialysis.

The reason for such good treatment effect of IgA Nephropathy is based on our clear understanding of the pathogenesis of this disease. What is IgA? It is a kind of immune globulin which is the guards of our body. IgA Nephropathy is often found after patient has an infection of catch a cold.

Low immunity and immune system disorder will cause IgA excessive formation within the body. Then they will deposit in the kidney mesangial area through the blood circulation. For the kidneys, the depositions are foreign substances and should be cleared out. This signal will result in disordered immune system, so the immune system will produce much inflammatory factors to clean the deposited IgA. As a result, excessive inflammatory reaction will cause the damage of renal intrinsic cells. So the kidney function will decrease. Finally, it progresses into End-Stage Kidney Failure.

Now we can see why the IgA Nephropathy will get worse. There are two reasons: 1) the deposited IgA can not be removed out of the body and it will cause the immune reaction over and over again. 2) the immune system have the defect. The immune blockers and steroids will also lower your immunity. The right treatment should aim at regulating the immunity but not restrain it.

For people with IgA Nephropathy who want to improve kidney function and avoid dialysis, they are suggested to find such an effective treatment with the following effects:

Adjusting immune system and let it recover to the normal function; Inhibiting excessive inflammatory recation; blocking the process of renal fibrosis progression.

Once these three aspects can be achieved, Renal Failure can be avoided. For person with IgA Nephropathy who want to know more about the specific treatment, you can consult our online service or email us at

  • Tag: IgA Nephropathy Treatment
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