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IgA Nephropathy: Chances of Having a Remission without Treatment

IgA Nephropathy: Chances of Having a Remission without Treatment"I have been diagnosed with IgA Nephropathy 3 weeks ago. My doctor told me more than 50% of my kidneys are scar tissue. Can you tell me my chances of having a remission without treatment?"

Actually, there is no definite answer to your question, because this has not been well researched. However, you can refer to the following information for a better understanding:

1. Remissions of IgA Nephropathy occur occasionally among pediatric patients, but it is extremely unlikely for adults to have spontaneous remission.

2. According to a study, about 4% of IgAN cases has been reported to have a spontaneous remission of all clinical symptoms. It it unknown whether this was paralleled by the spontaneous disappearance of IgA deposits in the kidneys, or by the restoration of normal glomerular structure.

3. The use of corticosteroid or other immunosuppressants may decrease chances of a natural remission.

As you have said you have lost over 50% of your renal function, you have developed into Stage 3 CKD with moderately reduced kidney function. Left untreated, you may experience gradually declined kidney function and eventually progress to End-Stage Renal Failure.

Our suggestions for you is to treat the disease from the root cause so as to prevent its development into Kidney Failure.

IgA Nephropathy is caused due to deposition of immune complexes in the mesangial area of kidneys when one's immune system is disordered. These immune complexes will trigger inflammatory response, leading to kidney damage.

For treating this disease, systemic treatment is needed to block the inflammatory reaction, clear up the immune complexes, and regulate the overall immune system. You can consult your doctor for such an effective treatment or refer to this article for more information: 'Biotherapy and Natural Remedy for IgA Nephropathy'.

  • Tag: IgA Nephropathy Basics
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